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CAS

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1248544-66-2

4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1248544-66-2 Structure

  • Basic information

    1. Product Name: 4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate
    2. Synonyms: 4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate
    3. CAS NO:1248544-66-2
    4. Molecular Formula:
    5. Molecular Weight: 577.701
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1248544-66-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate(1248544-66-2)
    11. EPA Substance Registry System: 4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)phenylcarbonyl)benzo[b]thiophen-2-yl)phenyl benzoate(1248544-66-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1248544-66-2(Hazardous Substances Data)

1248544-66-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1248544-66-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,8,5,4 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1248544-66:
(9*1)+(8*2)+(7*4)+(6*8)+(5*5)+(4*4)+(3*4)+(2*6)+(1*6)=172
172 % 10 = 2
So 1248544-66-2 is a valid CAS Registry Number.

1248544-66-2Relevant articles and documents

A mutant selective anti-estrogen is a pure antagonist on EREs and AP-1 response elements

Jain, Disha,Koh, John T.

supporting information; experimental part, p. 5258 - 5261 (2010/10/03)

Estrogen receptors (ERs) regulate gene transcription through classic estrogen response elements (EREs) as well as AP-1 responsive genes. The common SERMs Raloxifene, Tamoxifen, and ICI164384 function as ER antagonists on EREs but as ERβ agonists/partial agonists on AP-1 responsive genes. While developing a mutant selective analog of Raloxifene, that is an antagonist of ERα(E353A), we discovered an antagonist of wild-type ERα and ERβ that is also an antagonist of ERβ/AP-1 response. The analog, DRL527, represses basal AP-1 gene expression and antagonizes Raloxifene stimulated AP-1 expression. Therefore DRL527 has a unique, previously unreported, ERE/AP-1 activity profile.

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