1248591-75-4

Upstream product

• 1186210-21-8 5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester 
• 106-93-4 ethylene dibromide 

Downstream Products

• 1248591-78-7 5-[2-(1,3-dioxo-1,3-dihydroisoindol-2-yl)ethoxy]-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester 
• 1248591-79-8 5-[2-(3-cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)ethoxy]-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester 
• 1248591-80-1 5-[2-(3-cyano-4,6-dimethylpyridin-2-yloxy)ethoxy]-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester 
• 1353567-55-1 5-(2-benzoimidazole-1-yl-ethoxy)-3-methyl-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Novel anti-inflammatory agents based on pyrazole based dimeric compounds; design, synthesis, docking and in vivo activity

Series of pyrazole ester prodrugs analogues have been synthesized and found to contain highly potent inhibitors of the cyclooxygenase-2 (COX-2) enzyme. The paper describes synthesis of the target pyrazole analogues. The structure of the synthesized mutual