124957-75-1Relevant academic research and scientific papers
Stereoselective Synthesis of 3-Carboxy-4,5-dihydropyrroles via an Intramolecular Iminium Ion Cyclization Reaction
Xiang, Jinbao,Xie, Hongxiang,Li, Zhuo,Dang, Qun,Bai, Xu
supporting information, p. 3818 - 3821 (2015/08/18)
An efficient and practical method has been developed for the synthesis of trans-4,5-disubstituted 3-carboxy-4,5-dihydropyrroles via an intramolecular iminium ion cyclization reaction of readily accessible Baylis-Hillman derivatives and aldehydes in modera
Synthesis of chiral β2-amino acids by asymmetric hydrogenation
Luehr, Susan,Holz, Jens,Zayas, Odalys,Wendisch, Volkmar,Boerner, Armin
, p. 1301 - 1319 (2012/11/07)
The synthesis of chiral β2-amino acids by homogeneous asymmetric hydrogenation is discussed. Prochiral β-aryl- or β-hetaryl-α-N-benzyl/N-acetyl/N-Boc substituted α- aminomethylacrylates used as substrates were prepared by a Baylis-Hillman react
2-(N-Allylaminomethyl)cinnamaldehydes as substrates for syntheses of aza-polycycles via intramolecular cycloaddition reactions
Mishra, Amita,Rastogi, Neeraj,Batra, Sanjay
scheme or table, p. 2146 - 2154 (2012/03/27)
Syntheses of a variety of aza-polycycles employing 2-(N-allylaminomethyl) cinnamaldehydes derived from Morita-Baylis-Hillman adducts of acrylates via intramolecular 1,3-dipolar cycloaddition, or Aza-Diels-Alder or domino Knoevenagel/hetero Diels-Alder cyc
Water-promoted highly regio- and stereoselective synthesis of α-dehydro-β-amino esters and nitriles from Baylis-Hillman acetates
Ghosh, Sudip,Dey, Raju,Chattopadhyay, Kalicharan,Ranu, Brindaban C.
experimental part, p. 4892 - 4895 (2009/12/03)
The nucleophilic addition of amines to Baylis-Hillman acetates has been efficiently carried out in water at room temperature in the absence of any base, acid, or metal catalyst to produce α-dehydro-β-amino esters and nitriles. This procedure addresses a v
Cerium(IV) ammonium nitrate catalyzed synthesis of α-dehydro-β-amino esters
Paira, Moumita,Mandal, Samir Kumar,Roy, Subhas Chandra
, p. 2432 - 2434 (2008/09/20)
α-Dehydro-β-amino esters have been synthesized regioselectively from acetates of Baylis-Hillman adducts with amines in the presence of a catalytic amount of ceric ammonium nitrate (CAN) in good yield. The regioselectivity does not differ with respect to t
Regio- and stereoselective synthesis of α,β amino esters
Li, Dafeng,Li, Jian,Jia, Xueshun
experimental part, p. 434 - 436 (2009/06/30)
A facile method for the regio- and stereoselective synthesis of α,β-dehydro-β-amino esters from acetates of Baylis- Hillman adducts with amines was reported. In the absence of any solvent and catalyst, the present strategy works well for a series of electron deficient and electron rich aromatic amines as well as aliphatic ones.
A convenient route to β-amino propionic acid derivatives
Kundu, Mrinal K.,Bhat, Sujata V.
, p. 93 - 101 (2007/10/03)
A general convenient procedure for the synthesis of β-amino-propionic acid derivatives from Baylis-Hillman adducts is reported.
Preparation d'amines allyliques a partir d'acyloxy-3 methylene-2 propionates de methyle substitues en 3 par un groupement aromatique ou heteroaromatique
Foucaud, Andre,Guemmout, Farid El
, p. 403 - 408 (2007/10/02)
The reaction of substituted methyl 3-acetoxy 2-methylene propionates 2 with aliphatic amines gives allylic amines.The E configuration is predominant.The reaction of esters 2 with aniline does not give allylic amines.These amines are prepared by rearrangement of the carbamates which are obtained by the reaction of phenyl isocyanate with methyl 3-hydroxy 2-methylene propionates 1.The primary allylic amines are prepared through the reduction of azides 11.
