124958-74-3 Usage
Uses
Used in Pharmaceutical Synthesis:
Ethanone, 1-[5-fluoro-2-(methylamino)phenyl](9CI) is utilized as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure, which includes a fluorine atom and a methylamino group, contributes to the development of novel drug candidates with improved pharmacological properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Ethanone, 1-[5-fluoro-2-(methylamino)phenyl]- (9CI) serves as an important tool for studying the structure-activity relationship of drug molecules. By examining the effects of modifications to the Ethanone, 1-[5-fluoro-2-(methylamino)phenyl](9CI) structure, researchers can gain insights into the design of more effective and targeted therapeutic agents.
Used in Drug Development:
Ethanone, 1-[5-fluoro-2-(methylamino)phenyl](9CI) holds promise in the development of new medications and therapeutic agents. Its incorporation into drug candidates may enhance their efficacy, selectivity, and safety profiles, leading to innovative treatments for various diseases and conditions.
Used in Chemical Research and Development Industry:
Ethanone, 1-[5-fluoro-2-(methylamino)phenyl](9CI) is also employed in the broader chemical research and development industry, where it may be used to explore new chemical reactions, synthetic pathways, and the creation of novel chemical entities with potential applications in various fields, including materials science, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 124958-74-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,9,5 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 124958-74:
(8*1)+(7*2)+(6*4)+(5*9)+(4*5)+(3*8)+(2*7)+(1*4)=153
153 % 10 = 3
So 124958-74-3 is a valid CAS Registry Number.
124958-74-3Relevant academic research and scientific papers
TRICYCLIC AKR1C3 DEPENDENT KARS INHIBITORS
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, (2021/01/29)
The present invention relates to novel tricyclic compounds that are AKR1C3 dependent KARS inhibitor, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by an AKR1C3 dependent KARS inhibitor.
Copper-catalyzed intramolecular oxidative C(sp3)-H amidation of 2-aminoacetophenones: Efficient synthesis of indoline-2,3-diones
Huang, Jinbo,Mao, Tingting,Zhu, Qiang
supporting information, p. 2878 - 2882 (2014/05/20)
An efficient synthesis of diverse indoline-2,3-diones from 2-aminoacetophenones through copper-catalyzed intramolecular C(sp3)-H amidation is developed. The reaction proceeds in DMSO by using O2 as the sole oxidant to provide the desired products in moderate to good yields.
