124986-91-0Relevant academic research and scientific papers
A tandem organocatalytic α-chlorination-aldol reaction that proceeds with dynamic kinetic resolution: A powerful tool for carbohydrate synthesis
Bergeron-Brlek, Milan,Teoh, Timothy,Britton, Robert
supporting information, p. 3554 - 3557 (2013/08/23)
A tandem, proline-catalyzed α-chlorination/aldol reaction is described that involves a dynamic kinetic resolution of α-chloroaldehyde intermediates. The resulting syn-chlorohydrins are produced with good to excellent diastereoselectivity in high enantiopurity and provide new opportunities for the synthesis of carbohydrates.
