124991-99-7

Upstream product

• 33731-54-3 2,6-dimethyl-3,5-diphenyl-4H-pyran-4-one 
• 124945-37-5 2,6-Bis(brommethyl)-3,5-diphenyl-4-pyranon 
• 124945-43-3 9-Methoxy-16,18-diphenyl-2,11-dithia<3>metacyclo<3>(2,6)pyranophan-17-on 

Downstream Products

• 124945-47-7 8-Methoxy-14,16-diphenyl<2>metacyclo<2>(2,6)pyranophan-15-on 

Relevant academic research and scientific papers

Conformational Analyses of Phanes of 4-Pyranone Generated by Pyrolysis

The synthesis of the first phanes of 4-pyranone is accomplished by pyrolysis of bis(sulfone) 4.Analogously, 9, 10, and 11 are synthesized.While 5 is conformationally mobile in solution, 9 and 10 are fixed ( up to 100 deg C) and exhibit anti conformation as shown by X-ray structural analysis (9) and computer simulation of the 1H-NMR spectra (11).Like 9 and 11, 5 exists in a staircase-like structure in the crystal.The 1H-NMR spectra of the metaparacyclophane 10 shows coalescence of the signals of the methylene protons at room temperature.The flexibility of 10 at 60 deg C is interpreted as a swinging process.The crystal structure of bis(sulfone) 8a shows that the two planar rings are tilted by 60 deg C with respect to each other.