124994-40-7

Upstream product

• 123456-34-8 methyl 3-oxo-1,3-dihydroisobenzofuran-1-carboxylate 
• 706-07-0 1-chloro-4-(2-nitrovinyl)benzene 

Downstream Products

• 124994-44-1 (-)-1-<2-amino-1-(4-chlorophenyl)ethyl>-3-oxo-1,3-dihydroisobenzofuran-1-carboxylic acid hydrochloride 
• 124994-42-9 (-)-4'-(4-chlorophenyl)spiro-2',3-dione 
• 124994-44-1 (+)-1-<2-amino-1-(4-chlorophenyl)ethyl>-3-oxo-1,3-dihydroisobenzofuran-1-carboxylic acid hydrochloride 
• 124994-42-9 (+)-4'-(4-chlorophenyl)spiro-2',3-dione 

Relevant academic research and scientific papers

Potential GABAB Receptor Antagonists. II. Synthesis of 1--3-oxo-1,3-dihydroisobenzofuran-1-carboxylic Acid

Michael addition of methyl 3-oxo-1,3-dihydroisobenzofuran-1-carboxylate to nitrostyrenes is catalysed by amine bases.In non-polar solvents, the use of both enantiomers of ψ-ephedrine as base (0.1 equiv.) leads to both enantiomers, respectively, of a singl