706-07-0

Basic information

• Product Name: 1-(4-Chlorophenyl)-2-nitroethene
• Synonyms: 4'-CHLORO-BETA-NITROSTYRENE;4-CHLORO-BETA-NITROSTYRENE;1-CHLORO-4-(2-NITRO-VINYL)-BENZENE;1-(4-CHLOROPHENYL)-2-NITROETHENE;TRANS-4-CHLORO-BETA-NITROSTYRENE;p-chloro-beta-nitro-styren;p-chloro-beta-nitro-styrene;trans-4-chloro-β-nitrostyrene
• CAS NO: 706-07-0
• Molecular Formula: C₈H₆ClNO₂
• Molecular Weight: 183.59
• Product Categories: Ethanes/ethenes;Alkenyl;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 706-07-0.mol
• Article Data: 83

Chemical Properties

• Melting Point: 112-116 °C(lit.)
• Boiling Point: 299 °C at 760 mmHg
• Flash Point: 134.6 °C
• Appearance: /
• Density: 1.324 g/cm³
• Vapor Pressure: 0.00218mmHg at 25°C
• Refractive Index: 1.615
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(4-Chlorophenyl)-2-nitroethene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenyl)-2-nitroethene(706-07-0)
• EPA Substance Registry System: 1-(4-Chlorophenyl)-2-nitroethene(706-07-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-43
• Safety Statements: 36/37
• WGK Germany: 3
• RTECS: WL4200500
• HazardClass: IRRITANT
• Hazardous Substances Data: 706-07-0(Hazardous Substances Data)

Usage

General Description

1-(4-Chlorophphenyl)-2-nitroethene is a synthetic compound classified under the chemical category of aromatic halides and nitro compounds. It is known for its yellow to orange yellow crystalline form. This chemical has the molecular formula C8H6ClNO2 and a molecular weight of 185.59 g/mol, with chlorine, hydrogen, nitrogen, and oxygen as its constituent elements. It's mostly used in medical and chemical research due to its aromatic and nitro features. However, it's important to handle this compound with caution as it may present health hazards if improperly handled or ingested; it could potentially cause skin and eye irritation or damage to the respiratory system.

InChI:InChI=1/C8H6ClNO2/c9-8-3-1-7(2-4-8)5-6-10(11)12/h1-6H/b6-5+

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 75-52-5 nitromethane 
• 104-88-1 4-chlorobenzaldehyde 
• 1749-03-7 N-(4-chlorobenzylidene)-4-methoxyaniline 
• 1615-02-7 p-chlorocinnamic acid 
• 89979-04-4 1-(4-chlorophenyl)-2-nitroethanol 
• 1075-77-0 4-chlorocinnamaldehyde 
• 3395-81-1 4-chlorobenzaldehyde dimethyl acetal 
• 135711-37-4 Butyl-[1-(4-chloro-phenyl)-2-nitro-ethyl]-amine 

Downstream Products

• 107775-55-3 N-[1-(4-chloro-phenyl)-2-nitro-ethyl]-aniline 
• 10125-48-1 4-Chlor-1-<1,3,3-trinitro-butyl-2>-benzol 
• 10125-49-2 4-Chlor-1-(1,3,3-trinitropentyl-2)-benzol 
• 50368-40-6 5-(4-chloro-phenyl)-3-methyl-2-thioxo-[1,3,4]thiadiazinan-6-one oxime 
• 29651-84-1 S-1-(4-chlorophenyl)-2-nitroethyl thiolacetate 
• 82947-78-2 [1-(4-Chloro-phenyl)-2-nitro-ethyl]-phosphonic acid dipropyl ester 
• 82947-82-8 [2-(4-Chloro-phenyl)-2-(dipropoxy-phosphoryl)-ethyl]-phosphonic acid dipropyl ester 
• 92774-82-8 2-[1-(4-Chloro-phenyl)-2-nitro-ethyl]-3-hydroxy-cyclopent-2-enone 
• 82947-77-1 [1-(4-Chloro-phenyl)-2-nitro-ethyl]-phosphonic acid diisopropyl ester 
• 82947-81-7 [2-(4-Chloro-phenyl)-2-(diisopropoxy-phosphoryl)-ethyl]-phosphonic acid diisopropyl ester 
• 134541-93-8 2-Anilino-4-(4-chlorophenyl)-1-nitro-3-phenylcyclobutene 
• 77484-23-2 dichloro-3,6 indolinone-2 
• 77484-33-4 acide N-acetyl chloro-2 (p.chlorophenyl)-2 acetohydroxamique 
• 77484-43-6 chlorure de l'acide N-acetoxy chloro-2 (p.chlorophenyl)-2 acetohydroximique 

Relevant articles and documents

Microwave-assisted rapid synthesis of spirooxindole-pyrrolizidine analogues and their activity as anti-amyloidogenic agents

A library of Sox-pyrrolizidines was rapidly prepared by microwave-assisted, one-pot, three-component, 1,3-dipolar cycloaddition of azomethine ylides from l-proline and isatin, with various β-nitrostyrenes. Nitro-Sox compounds, 4b, 4d and 4e inhibit HEWL amyloid fibril formation by ThT studies with percentages of fluorescence intensity of 55.4, 42.9 and 40.3%, respectively. Further studies with MTT assay, Raman spectroscopy, TEM and molecular docking supported these promising candidates for activity against amyloid misfolding, a phenomenon leading to Alzheimer's disease pathology.

A green metal-free "one-pot" microwave assisted synthesis of 1,4-dihydrochromene triazoles

The synthesis of several 4-aryl-1,4-dihydrochromene-triazoles was achieved via a metal-free "one-pot"procedure using PEG400 as the sole solvent in an eco-friendly process. Using microwave irradiation, the triazole derivatives were obtained in good yields and short reaction times starting from readily accessible building blocks.

Skeletally Tunable Seven-Membered-Ring Fused Pyrroles

We describe a copper-mediated method that enables the synthesis of seven-membered-ring fused pyrroles (7-mrFPs). The protocol proceeds via an in situ spiro-intermediate ring expansion and tolerates a library of 7-mrFP derivatives with a broad range of functional groups in a simple step with tangible parameters and substrate adaptations. These rare 7-mrFPs are now accessible on a millimolar scale, and selected examples exhibit high antioxidant activity.