125-46-2

Usage

Uses

Used in Antitumor Applications:
USNIC ACID is used as an antitumor agent for its enzyme-inhibiting properties, potentially offering therapeutic benefits in cancer treatment.
Used in Antibacterial Applications:
USNIC ACID is utilized as an antibacterial agent, providing a natural alternative for combating bacterial infections.
Used in Pharmaceutical Research:
USNIC ACID is used as an important metabolite in dereplication for discovery research programs, aiding in the identification and characterization of novel bioactive compounds.
Used in Drug Delivery Systems:
Although not explicitly mentioned in the provided materials, USNIC ACID's potential applications in drug delivery systems could be explored, similar to gallotannin, to enhance its delivery, bioavailability, and therapeutic outcomes in various medical applications.

Contact allergens

Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers.

Purification Methods

This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.]

InChI:InChI=1/C18H16O7/c1-6-14(22)12(8(3)20)16-13(15(6)23)18(4)10(25-16)5-9(21)11(7(2)19)17(18)24/h5,21-23H,1-4H3/t18-/m0/s1

Downstream Products

• 62495-85-6 8-acetyl-5,7-dihydroxy-3,4a,6-trimethyl-1-phenyl-1,4a-dihydro-4H-benzofuro[3,2-f]indazol-4-one 

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Thymol and usnic acid as the important secondary metabolites of respectively Artemisia haussknechtii and Protoparmeliopsis muralis were used for reduction and stabilizing of AgNO3 and CuSO4 in metal nanoparticles (MNPs) biosynthesis process. Antibacterial effects of prepared Ag-thymol (ATNPs), A...detailed

USNIC ACID (cas 125-46-2) reactive metabolites formation in human, rat, and mice microsomes. Implication for hepatotoxicity09/26/2019

Usnic acid is a lichen compound which is extensively studied due to its cytotoxic, antiproliferative, antimicrobial, antiviral, antiprotozoal, and anti-inflammatory activities. Despite a broad spectrum of biological properties, usnic acid is a hepatotoxic agent, thus its potential use as a drug ...detailed

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