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CAS

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125-72-4

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125-72-4 Usage

Uses

Orally active synthetic morphine analog. Analgesic (narcotic). Controlled substance.

Brand name

Levo-Dromoran (Valeant).

Clinical Use

Levorphanol is a potent μ agonist (approximately sixfold greater than morphine), and its uses, side effects, and physical dependence liability are like those of oxymorphone or hydromorphone. Levorphanol is available in oral, subcutaneous, and intravenous dosage forms. The oral dose of levorphanol is approximately twice the parenteral dose. This drug is unique among the μ agonists in that its analgesic duration of action is 4 to 6 hours, whereas its clearance half-life is 11.4 hours. Thus, effective analgesic doses of this agent can lead to a buildup of the drug in the body and result in excessive sedation.

Check Digit Verification of cas no

The CAS Registry Mumber 125-72-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,2 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 125-72:
(5*1)+(4*2)+(3*5)+(2*7)+(1*2)=44
44 % 10 = 4
So 125-72-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;/m0./s1

125-72-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name l-DROMORAN TARTRATE

1.2 Other means of identification

Product number -
Other names Levo-Dromoran

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125-72-4 SDS

125-72-4Relevant articles and documents

METHODS FOR PREPARING LEVORPHANOL AND RELATED COMPOUNDS, AND COMPOSITIONS THEREOF

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Paragraph 0177-0182, (2020/04/29)

A method for producing substantially pure levorphanol and related compounds, when compared to the conventional process, is provided. In particular, a method for producing substantially pure levorphanol tartrate dihydrate is described. Also described are compositions comprising levorphanol and related compounds, particularly compositions comprising levorphanol tartrate dihydrate, levomethorphan, and norlevorphanol in which the levomethorphan and norlevorphanol are present in the composition in reduced levels.