125013-08-3

Upstream product

• 125013-05-0 [(3R,4R)-3-Bromo-2-oxo-4-(2-oxo-ethyl)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-methoxy-benzyl ester 
• 125013-04-9 (3'R,4'R)-p-methoxybenzyl (4'-allyl-3'-bromo-2'-oxoazetidin-1'-yl)(triphenylphosphoranylidene)acetate 
• 138477-43-7 ((2R,3R)-2-Allyl-3-bromo-4-oxo-azetidin-1-yl)-hydroxy-acetic acid 4-methoxy-benzyl ester 
• 125013-06-1 (5R,6R)-p-methoxybenzyl 6-bromo-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 87791-44-4 (3R,4R)-4-allyl-3-bromoazetidin-2-one 
• 64370-70-3 4-methoxybenzyl glyoxylate 
• 108-24-7 acetic anhydride 

Downstream Products

• 125013-09-4 (5R)-p-methoxybenzyl 6-<(E)-(1-methyl-1H-1,2,3-triazol-4-yl)methylene>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 
• 125013-10-7 (5R)-p-methoxybenzyl 6-<(Z)-(1-methyl-1H-1,2,3-triazol-4-yl)methylene>-7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate 

Relevant academic research and scientific papers

SYNTHESIS OF (5R) (E)-6-((1-METHYL-1,2,3-TRIAZOL-4-YL)METHYLENE)-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-ENE-CARBOXYLIC ACID, A NOVEL CARBAPENEM DERIVATIVE, FROM 6-AMINOPENICILLANIC ACID

The title compound has been prepared from 6-aminopenicillanic acid via the novel intermediate, p-methoxybenzyl (5R,6R) 6-bromo-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate (10).