125016-58-2Relevant academic research and scientific papers
Lewis acid mediated addition of 2-acyl-1,3-dithianes to α,β-unsaturated ketones: Synthesis of cyclohexenedione mono-dithioacetals
Bulman Page, Philip C.,Marchington, Allan P.,Graham, Lisa J.,Harkin, Shaun A.,Wood, William W.
, p. 10369 - 10386 (1993)
2-Acyl-1,3-dithianes undergo Lewis acid-mediated conjugate addition to α,β-unsaturated ketones to provide 1,5-diketones which suffer base-catalyzed intramolecular aldol reaction to produce monodithioacetals of cyclohex-2-en-1,4-diones and cyclohex-3-en-1,
ADDITION OF AMINOKETENE DITHIOACETALS TO α,β-UNSATURATED KETONES. SYNTHESIS AND REACTIONS OF CYCLOHEX-2-EN-1,4-DIONE MONODITHIOACETALS
Page, Philip C. Bulman,Harkin, Shaun A,Marchington, Allan P.,Niel, Monique B. van
, p. 3819 - 3838 (2007/10/02)
Aminoketene dithioacetals add to α,β-unsaturated ketones to give 1,5-diketones after hydrolytic work-up.Upon treatment with acid or base, these diketones suffer intramolecular aldol reactions yielding cyclohex-2-en-1,4-dione monodithioacetals, interesting and useful synthetic equivalents of cyclohex-2-en-1,4-diones which readily undego conjugate addition and cycloaddition reactions.
