125041-28-3Relevant academic research and scientific papers
Substituted Pyrazoles as Ghrelin Receptor Antagonists
-
Page/Page column 26-27, (2009/10/17)
Certain novel N-acylated spiropiperidine derivatives are ligands of the human ghrelin receptor(s) and, in particular, are antagonists/inverse agonists of the human ghrelin receptor. They are therefore useful for the treatment, control, or prevention of di
SUBSTITUTED PYRAZOLES AS GHRELIN RECEPTOR ANTAGONISTS
-
Page/Page column 46, (2008/06/13)
Certain novel N-acylated spiropiperidine derivatives are ligands of the human ghrelin receptor(s) and, in particular, are antagonists/inverse agonists of the human ghrelin receptor. They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of the ghrelin receptor, such as obesity, diabetes, and metabolic syndrome.
New Syntheses of Pyrazolopyrimidine, Pyrazolopyridazine, Isoindolinedione and Pyrazole Derivatives
Abdelhamid, Abdou O.,Negm, Abdalla M.,Abbas, Ikhlass M.
, p. 31 - 36 (2007/10/02)
Phenacylmalononitriles 2 react with hydrazines, acetic-hydrochloric acid and with diazotised primary aromatic amines to afford phenacylpyrazole (5a,b), aminofurans (6a,b) and aminopyrazole derivatives (3a,d) respectively.The synthesised derivatives (3d,6a
