1250436-91-9Relevant academic research and scientific papers
Microwave assisted transformation of benzimidazolyl chalcones into N 1-substituted pyrazolines and evaluation of their antimicrobial activities
Rajora, Jayanti,Yadav, Janardan,Kumar, Ravindra,Srivastava, Yogendra K.
experimental part, p. 989 - 993 (2010/11/03)
1-Benzimidazolyl-3-aryl-prop-2-ene-1-ones 2 have been transformed into N1-substituted pyrazoline derivatives by the interaction with phenyl hydrazine, thiosemicarbazide and hydrazine hydrate in the presence of formic acid under solvent microwave induced protocol. The structure of newly synthesized compounds have been confirmed on the basis of their elemental analysis and spectral data. Newly synthesized compounds have been evaluated for their antimicrobial activity in against E. coli, K. pneumonae, P. aeruginosa and B. subtilis using paper disc method. Some of the compounds have shown significant activity against the pathogens.
