125069-77-4Relevant academic research and scientific papers
A Convergent Synthesis of Symmetrical Carotenoids Using the Heck Reaction
Bienayme, Hugues
, p. 6867 - 6868 (1994)
Regioselective Heck-type vinylation of various allylic alcohols with 2, followed by an acidic dehydration, delivers symmetrical carotenoids in good yields. - Key words: Heck vinylation; Palladium; Carotenoids; β-Carotene
Regio- and stereochemistry in the sequential insertion of carbonyl compounds into zirconium-diene complexes
Yasuda, Hajime,Okamoto, Takuji,Mashima, Kazushi,Nakamura, Akira
, p. 61 - 76 (2007/10/02)
Group 4 metal-diene complexes of the type Zr(η-C5H5)2(s-cis-diene) and Zr(η-C5H5)2(s-trans-diene) (diene=butadiene, isoprene, pentadiene and their derivatives) were found to undergo regioselective 1/1 addition with a variety of aldehydes, ketones, esters and acid amides at the sterically more crowded terminal carbon of the ligated diene to give the (Z)-oxazirconacyclo-4-heptenes.Further addition of carbonyl compounds to the resulting oxametallacycle leads to 1/2 adducts of (E)-1,3-dioxazircona-6-nonene structure when the precursor oxazirconacycloheptene has a less bulky hydrogen group at the C(5) position.Highly selective, three-component, sequential addition was first realized by treatment of a ketone or an aldehyde with Zr(C5H5)2(diene)/ester, Zr(C5H5)2(diene)/alkene and Zr(C5H5)2(diene)/alkyne adducts.
