1250978-97-2Relevant articles and documents
Application of a process friendly morpholine synthesis to (S,S)-Reboxetine
Assaf, Georges,Cansell, Gemma,Critcher, Doug,Field, Stuart,Hayes, Stewart,Mathew, Suju,Pettman, Alan
scheme or table, p. 5048 - 5051 (2011/01/12)
We report our results on the construction of a morpholine ring system from the corresponding epoxide and amino alcohol. From this study, we were able to convert a previous four-step synthesis into a more efficient two-step process.