125144-96-9Relevant academic research and scientific papers
The hemilabile behaviour of alkyl diphenylphosphinoacetate ligands promoting the reversible coordination of small molecules on (η6-arene)ruthenium(II) centres
Demerseman, Bernard,Renouard, Corinne,Lagadec, Ronan Le,Gonzalez, Marta,Crochet, Pascale,Dixneuf, Pierre H.
, p. 229 - 240 (2007/10/02)
Complexes 6-arene)1-Ph2PCH2C=O)OR>RuCl2> have been prepared.Easy methanolysis and hydrolysis of the ester function occur when R=t-Bu.When R=Me, the stability of the ester function allows the synthesis of the stable salts 6-arene)2-Ph2PCH2C(=O)OMe>RuCl>X (X=PF6 or BF4).Preparation of 6-arene)(L)1-Ph2PCH2C(=O)OMe>RuCl>+ (L=Me2S, MeCN or t-BuCN) from η1-P- and η2-(P,O)-methyl phosphinoacetate derivatives has been studied and the strength of both the L and ester ruthenium coordinative bonds compared.The reactivity of these functional phosphine complexes differs markedly from that of the homologous compounds 6-arene)(PMe3)RuCl2>,6-arene)RuCl2> and 6-arene)2-Ph2PC(R)=C(R')O>RuCl.Competitive and reversible coordination of dimethylsulfide and nitriles or of the ester function is observed and a change in the arene produces selectivity in the coordination of dimethylsulfide and nitriles.Key words: Ruthenium; Iron; Phosphine; Arene
SYNTHESIS OF SOME FUNCTIONALIZED PHOSPHINOCARBOXYLIC ACIDS
van Doorn, J. A.,Meijboom, N.
, p. 211 - 222 (2007/10/02)
Various functionalized phosphinocarboxylic acids have been prepared by a number of complementary methods.Reactions of relatively electron-poor secondary phosphides with electron-rich halocarboxylates in liquid ammonia give high yields of phosphinocarboxylates.The substitution reactionmay proceed by a classical SN2 mechanism or by an SN rad mechanism.Reduction of the carboxilate can be a deleterious side reaction in the preparation of phosphinoacetic acids.Several phosphinopropionic acids are prepared by the Michael adition of diphenylphosphine to unsaturated esters.A valuable method proved to be the reaction of dichlorophosphinoacetic ester with functionalized organometallic reagents. Key words: Phosphine; carboxylic acid; ligand; functionalized; synthesis; NMR data.
