3064-56-0

Usage

Uses

Used in Pharmaceutical and Fine Chemicals Production:
Carboxymethyldiphenylphosphine is utilized as a ligand in transition metal-catalyzed reactions, specifically in palladium-catalyzed cross-coupling reactions. It plays a crucial role in the synthesis of complex organic molecules, which are essential in the production of pharmaceuticals and fine chemicals.
Used in Material Science:
In the field of material science, Carboxymethyldiphenylphosphine is employed in the preparation of advanced materials with tailored properties. Its unique structure and reactivity allow for the development of materials with specific characteristics, which can be applied in various high-tech applications.
Used in Organic Synthesis:
Carboxymethyldiphenylphosphine is used as a reagent in organic synthesis for its ability to facilitate specific chemical transformations. Its presence can improve the yield and selectivity of reactions, making it a valuable tool in the synthesis of complex organic compounds.

InChI:InChI=1/C14H13O2P/c15-14(16)11-17(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H,11H2,(H,15,16)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 829-85-6 diphenylphosphane 
• 124-38-9 carbon dioxide 
• 1486-28-8 diphenyl(methyl)phosphine 
• 107-59-5 tert-Butyl chloroacetate 
• 65567-06-8 lithium diphenylphosphide 
• 62263-69-8 (lithiomethyl)diphenylphosphane 
• 96-34-4 methyl chloroacetate 
• 79-11-8 chloroacetic acid 
• 3926-62-3 sodium monochloroacetic acid 
• 603-35-0 triphenylphosphine 
• 125144-96-9 t-butyl diphenylphosphinoacetate 
• 125144-97-0 Diphenylphosphanyl-acetic acid phenyl ester 

Downstream Products

• 121232-21-1 (-)-(1S)-<(1α,2α,5α)-4,6,6-trimethylbicyclo<3.1.1>hept-3-en-2-yl> (diphenylphosphino)acetate 
• 144681-50-5 (+)-(1S)-<(1α,2β,5α)-4,6,6-trimethylbicyclo<3.1.1>hept-3-en-2-yl> (diphenylphosphino)acetate 
• 121232-20-0 3a,4,5,6,7,7a-hexahydro-(1α,3aα,4α,7α,7aα)-4,7-methano-1H-inden-1-yl (diphenylphosphino)acetate 
• 144681-47-0 4-cholesten-3α-yl (diphenylphosphino)acetate 
• 144681-46-9 4-cholesten-3β-yl (diphenylphosphino)acetate 
• 121232-23-3 (+)-(R)-(E)-(4-phenyl-3-buten-2-yl) (diphenylphosphino)acetate 
• 121232-18-6 methyl cis-<5-(diphenylphosphino)acetoxy-3-cyclohexene-1-carboxylate> 
• 124-38-9 carbon dioxide 
• 1486-28-8 diphenyl(methyl)phosphine 
• 188790-94-5 2-Diphenylphosphanyl-1-((S)-3-diphenylphosphanyl-pyrrolidin-1-yl)-ethanone 
• 113622-44-9 chlorobis(diphenylphosphinoacetato)(diphenylphosphinoacetic acid)rhodium(III) 
• 116722-83-9 bis(diphenylphosphinoacetato)diphenylphosphinoacetic acid ruthenium(II) 
• 114631-71-9 (diphenylphosphinoacetato)(diphenylphosphinoacetic acid)triphenylphosphinerhodium(I) 
• 92763-44-5 (diphenylphosphinoacetato)(diphenylphosphinoacetic acid)carbonylrhodium(I) 

Relevant academic research and scientific papers

SYNTHESIS OF SOME FUNCTIONALIZED PHOSPHINOCARBOXYLIC ACIDS

Various functionalized phosphinocarboxylic acids have been prepared by a number of complementary methods.Reactions of relatively electron-poor secondary phosphides with electron-rich halocarboxylates in liquid ammonia give high yields of phosphinocarboxylates.The substitution reactionmay proceed by a classical SN2 mechanism or by an SN rad mechanism.Reduction of the carboxilate can be a deleterious side reaction in the preparation of phosphinoacetic acids.Several phosphinopropionic acids are prepared by the Michael adition of diphenylphosphine to unsaturated esters.A valuable method proved to be the reaction of dichlorophosphinoacetic ester with functionalized organometallic reagents. Key words: Phosphine; carboxylic acid; ligand; functionalized; synthesis; NMR data.

A Simple Synthesis and Some Synthetic Applications of Substituted Phosphide and Phosphinite Anions

Based on data for the acidity relationship of phosphines and phosphinous acids and water in dimethyl sulfoxide and water, a simple method is reported for the generation of phosphide and phosphinite anions by the action of concentrated aqueous alkali on primary and secondary phosphines as well as phosphinous acids in dimethyl sulfoxide or other dipolar aprotic solvents.Alkylation of the anion yields secondary and tertiary phosphines, polyphosphines, functionally substituted phosphines as well as similarly substituted phosphine oxides.Phosphinous acids have beenalkylated in various solvents in two-phase systems containing concentrated aqueous alkali and tetrabutylammonium iodide as phase transfer catalyst.