1251457-89-2

Upstream product

• 1251457-88-1 benzyl 5-(3-(hydroxymethyl)-5-(trifluoromethyl)benzyl)-2,3-dihydro-1H-inden-1-ylcarbamate 

Downstream Products

• 1251457-58-5 N-(5-(3-(hydroxymethyl)-5-(trifluoromethyl)benzyl)-2,3-dihydro-1H-inden-1-yl)thiophene-2-sulfonamide 
• 1251457-63-2 2,2,2-trifluoro-N-(5-(3-(hydroxymethyl)-5-(trifluoromethyl)benzyl)-2,3-dihydro-1H-inden-1-yl)acetamide 
• 1251457-64-3 (3-(trifluoromethyl)-5-((1-((3-(trifluoromethyl)pyridin-2-yl)methylamino)-2,3-dihydro-1H-inden-5-yl)methyl)phenyl)methanol 

Relevant academic research and scientific papers

INDANE DERIVATIVES

The present invention relates to anindane derivative according to formula I wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said indane derivatives and to their use in therapy, for instance in the treatment or prevention of psychiatric diseases where an enhancement of synaptic responses mediated by AMPA receptors is required, including schizophrenia, depression and Alzheimer' s disease.