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4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide, commonly referred to as NQO1, is a chemical compound characterized by its high reactivity and the ability to generate harmful free radicals within biological systems. It is a significant molecule in the realm of scientific research, particularly in the study of its impact on cellular and tissue health, as well as its role in detoxification and cellular regulation processes.

125162-98-3

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125162-98-3 Usage

Uses

Used in Research Applications:
4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide is utilized as a research tool in laboratory settings to investigate its effects on cells and tissues. It aids in understanding the mechanisms of detoxification and the regulation of cellular processes, as well as the potential pathological implications of excessive NQO1 production.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide is used as a compound of interest for the development of drugs targeting detoxification pathways and the modulation of cellular processes. Its role in the development of certain diseases, such as cancer, where it can contribute to the accumulation of reactive oxygen species, makes it a potential target for therapeutic intervention.
Used in Toxicology Studies:
4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide is employed in toxicology to study the effects of free radicals and oxidative stress on biological systems. Understanding its impact can help in the development of strategies to mitigate the harmful effects of reactive oxygen species and their contribution to disease progression.
Used in Environmental Monitoring:
In environmental science, 4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide may be used to monitor and assess the presence of harmful substances in the environment that could potentially lead to the production of this reactive compound, thereby indicating areas of concern for public health and environmental safety.

Check Digit Verification of cas no

The CAS Registry Mumber 125162-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,1,6 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 125162-98:
(8*1)+(7*2)+(6*5)+(5*1)+(4*6)+(3*2)+(2*9)+(1*8)=113
113 % 10 = 3
So 125162-98-3 is a valid CAS Registry Number.

125162-98-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-nitro-1-oxido-5,6,7,8-tetrahydroquinolin-1-ium

1.2 Other means of identification

Product number -
Other names 4-Nitro-5,6,7,8-tetrahydroquinoline 1-oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125162-98-3 SDS

125162-98-3Downstream Products

125162-98-3Relevant academic research and scientific papers

PYRIDINE DERIVATIVES

-

, (2008/06/13)

Pyridine derivatives of formula STR1 their heteroaromatic N-oxides and their pharmaceutically acceptable acid addition salts are disclosed. In the formula z is 0, 1 and 2 and R, R 1, R 2 and R. sup.2 have specified meanings. The compounds exhibit activity

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