1251736-38-5Relevant articles and documents
Pd2(dba)3-promoted synthesis of 3-N-substituted 4-aryl-1,2,3,6-tetrahydropyridine
Chang, Meng-Yang,Lin, Chung-Han,Chen, Yeh-Long,Hsu, Ru-Ting,Chang, Ching-Yao
experimental part, p. 4886 - 4889 (2010/10/02)
A novel method for the synthesis of 3-N-substituted 4-aryl-1,2,3,6- tetrahydropyridine 3 is presented. The process is carried out by the allylic bromination of 4-aryl-1,2,3,6-tetrahydropyridines 1 with N-bromosuccinimide in propanoic acid and palladium-catalyzed cross coupling of the corresponding bromide 2 with different N-based nucleophiles.