125184-69-2

Upstream product

• 125184-77-2 (3R,3aS)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid methyl ester 
• 125184-66-9 (1S,2R,4S,5R)-8-Benzyloxy-3,3-dimethyl-1-morpholin-4-yl-tricyclo[3.3.0.0^2,4]octane-2-carboxylic acid methyl ester 
• 125184-78-3 {(3R,3aS)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-methanol 
• 125184-67-0 (3R,3aS)-6-Benzyloxy-3-hydroxy-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid methyl ester 
• 101836-59-3 4-(5-Benzyloxy-cyclopent-1-enyl)-morpholine 
• 103588-79-0 (1,1,2,2-tetramethyleth-1-yl)-dimethylsilyl trifluoromethanesulfonate 
• 21603-22-5 1-carbomethoxy-3,3-dimethylcyclopropene 
• 42201-74-1 <β-(Trimethylsilyl)vinyl>magnesium bromide 
• 125184-68-1 (3R,3aS)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carbaldehyde 
• 131694-73-0 (3R,3aS)-3-Hydroxy-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid ethyl ester 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 42201-74-1 2-trimethylsilylethenylmagnesium bromide 
• 125184-68-1 (3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carbaldehyde 
• 134747-96-9 (3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid ethyl ester 

Downstream Products

• 125184-70-5 (E)-1-{(3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-3-trimethylsilanyl-propenone 
• 125184-70-5 (E)-1-{(3R,3aS)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-3-trimethylsilanyl-propenone 

Relevant academic research and scientific papers

The cyclobutenic way to triquinanes. Synthesis of (±) silphinene

The easily accessible alcohol 2 is oxidized, after protection, to the allylic alcohol 3. The benzyl ether of this diquinanic alcohol is transformed into the triquinanic precursor 9 of (±) Silphinene, using a similar reaction sequence as described previous

SYNTHESE CYCLOPROPENIQUE TOTALE D'UN TRIQUINANE NATUREL ANGULAIRE, LE (+/-)-SILPHINENE

(+/-)-Silphinene, a natural angular triquinane has been synthesized, starting from 3,3-dimethyl-methoxycarbonylcyclopropene.The ring A of the skeleton results from the cycloaddition of the cyclopropene with the enamine 1, followed by solvolytic ring cleav