1252003-15-8 Usage
Definition
ChEBI: A pyridoindole that is 1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indole which is substituted on the tetrahydropyridine nitrogen by a methyl group and on the indole nitrogen by a p-[N-(hydroxy)aminoca
bonyl]benzyl group. It is a histone deacetylase 6 (HDAC6) inhibitor that is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold).
Check Digit Verification of cas no
The CAS Registry Mumber 1252003-15-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,2,0,0 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1252003-15:
(9*1)+(8*2)+(7*5)+(6*2)+(5*0)+(4*0)+(3*3)+(2*1)+(1*5)=88
88 % 10 = 8
So 1252003-15-8 is a valid CAS Registry Number.
1252003-15-8Relevant articles and documents
HDAC6 inhibitor accelerates wound healing by inhibiting tubulin mediated IL-1β secretion in diabetic mice
Ghosh, Balaram,Goli, Sriharshini,Karnam, Kalyani,Kulkarni, Onkar Prakash,Routholla, Ganesh,Sedmaki, Kavitha,Sharma, Pravesh,Venuganti, Venkata Vamsi Krishna
, (2020/08/06)
Delayed wound healing in diabetes is characterized by sustained activation of inflammasome and increased expression of IL-1β in macrophages. Identification and validation of novel pathways to regulate IL-1β expression will provide therapeutic targets for
