1252009-20-3

Upstream product

• 914366-93-1 (E,4S,5S)-ethyl 7-(benzyloxy)-5-hydroxy-4-methylhept-2-enoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 872369-16-9 (?)-(2S,3S)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentan-1-ol 
• 872369-17-0 (2R,3S)-5-(benzyloxy)-3-(tert-butyldimethylsilyloxy)-2-methylpentanal 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 1252009-22-5 (4S,5S,E)-7-(benzyloxy)-5-((tert-butyldimethylsilyl)oxy)-4-methylhept-2-en-1-ol 

Relevant academic research and scientific papers

Synthetic studies toward the marine metabolite prorocentin-4: Synthesis of the C1-C23 fragment

A synthetic study of the construction of the C1-C23 fragment of prorocentin-4, a novel linear polyketide, is described. The synthetic highlights include the acid catalyzed epoxide opening, Gilman reaction, Pd(OH)2 catalyzed transformation of a

Synthetic studies on cytotoxic macrolides cruentarens A and B: Stereoselective synthesis of the C8C19 segment of cruentarens A and B

A stereoselective synthesis of the C8C19 segment of cruentarens A and B, cytotoxic natural products, has been accomplished. The key steps involve a stereoselective radical cyclization, stereospecific methylation of a c, d-epoxy acrylate, nucleophilic epoxide ring opening and a cis-Wittig olefination.