125217-05-2Relevant academic research and scientific papers
The Chemistry of Phthalide-3-carboxylic Acid. VI The Stereochemistry of Some 3-Amino(aryl)methylphthalides and the Derived 3-Aryl-4-hydroxy-3,4-dihydroisoquinolin-1(2H)-ones
Collins, Peter R.,Janowski, Wit K.,Prager, Rolf H.
, p. 549 - 560 (2007/10/02)
The isomeric 3-isobenzofuran-1(3H)-ones, of known configuration, have been converted into the corresponding amino and dimethylamino compounds with inversion of configuration, and hence the stereochemistry of these compounds has been
A FACILE SYNTHESIS OF PHTHALIDEISOQUINOLINES BY DECARBOXYLATION OF PHTHALIDECARBOXYLATES IN THE PRESENCE OF IMINE METHIODIDES
Chiefari, John,Janowski, Wit K.,Prager, Rolf H.
, p. 863 - 867 (2007/10/02)
Decarboxylation of potassium phthalide-3-carboxylates in the presence of acyclic imine methiodides in DMSO leads mainly to 2-acylbenzamides, but with 3,4-dihydroisoquinolinium methiodides, a one step synthesis of phthalideisoquinolines is achieved in mode
