125249-74-3Relevant academic research and scientific papers
Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one
Beres,Sagi,Tomoskozi,Gruber,Baitz-Gacs,Otvos,De Clercq
, p. 1353 - 1360 (2007/10/02)
Enantiomerically pure (+)- and (-)-carbocyclic thymidine, (-)-carbocyclic 3'-epi-thymidine, (+)-carbocyclic 3'-deoxy-3'-azidothymidine, (+)-carbocyclic 2,3'-O-anhydrothymidine, (+)-carbocyclic 3'-O,6'-methylenethymidine, and (+)-(6'S)-carbocyclic 6'-methy
SYNTHETIC STUDIES TOWARDS (-)-CARBA-3'-DEOXY-3'-FLUOROTHYMIDINE
Beres, J.,Sagi, Gy.,Baitz-Gacs, E.,Toemoeskoezi, I.,Gruber, L.,Oetvoes, L.
, p. 6271 - 6280 (2007/10/02)
Stereospecific synthesis of (-)-carba-3'-deoxy-3'-fluorothymidine (-)-11 is reported from the protected (-)-carbocyclic 3'-epi-thymidine (-)-7 using diethylaminosulfur trifluoride.Under the conditions used, extensive dehydration of the blocked precursor i
