125272-41-5

Basic information

• Product Name: C₄₆H₅₄N₇O₆P
• CAS NO: 125272-41-5
• Molecular Weight: 831.952
• Mol File: 125272-41-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₄₆H₅₄N₇O₆P(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₆H₅₄N₇O₆P(125272-41-5)
• EPA Substance Registry System: C₄₆H₅₄N₇O₆P(125272-41-5)

Safety Data

• Hazardous Substances Data: 125272-41-5(Hazardous Substances Data)

Upstream product

• 685-83-6 bis(diethylamino)chlorophosphine 
• 64325-78-6 N₆-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine 
• 2283-11-6 hexaethylphosphoric triamide 

Downstream Products

• 104684-74-4 C₃₈H₃₆N₅O₈P 

Relevant articles and documents

A simple Preparation of 5'-O-dimethoxytrityl Deoxyribonucleoside 3'-O-Phosphorbisdiethylamidites as Useful Intermediates in the Synthesis of Oligodeoxyribonucleotides and Their Phosphorodiethylamidate Analogs on a Solid Support

5'-O-Dimethoxytrityl deoxyribonucleoside 3'-O-phosphorbisdiethylamidites were prepared by the selective phosphitylation of 5'-O-dimethoxytrityl deoxyribonucleosides with tris(diethylamino)phosphine in the presence of amine and tetrazol as catalyst.The bisamidites activated by p-nitrophenyltetrazole can be coupled efficiently with 5'hydroxyl group of nucleoside on a solid support.Oligodeoxyribonucleotides were obtined in high yields.The phosphorodiethylamidate linkage was obtained by non-aqueous oxidation using tert-butyl hydroperoxyde of the phosphordiethylamidite formed after the coupling.