125280-32-2Relevant academic research and scientific papers
Asymmetric transfer hydrogenation of prochiral ketones in aqueous media with new water-soluble chiral vicinal diamine as ligand
Ma, Yaping,Liu, Hui,Chen, Li,Cui, Xin,Zhu, Jin,Deng, Jingen
, p. 2103 - 2106 (2003)
(Matrix presented) An easily accessible water-soluble chiral o-sulfonated 1,2-diphenylethlenediamine 2 and its mono-N-tosylated derivative 3 were synthesized for the first time. The ruthenium-complex-catalyzed reduction of prochiral ketones in aqueous media has been examined by using 3 as ligand and sodium formate as the source of hydrogen. The asymmetric transfer hydrogenation of ω-bromo acetophenones was achieved, in which only formate displacement occurred when formic acid/triethylamine azeotrope was used as the hydrogen donor.
First example of hydrolytic kinetic resolution of acrylate of secondary alcohols by lipase Amano AK
Bora, Pranjal P.,Bez, Ghanashyam,Anal, Jasha Momo H.
, p. 270 - 275 (2012/07/03)
Lipase Amano AK is found to be extremely efficient catalyst for hydrolytic kinetic resolution of acrylates of secondary alcohols in aqueous phosphate buffer at pH 7.0. Both aliphatic and benzylic secondary alcohols show good to excellent E values.
Reduction of Aromatic Nitro Compounds with Baker's Yeast
Takeshita, Mitsuhiro,Yoshida, Sachiko,Kiya, Rieko,Higuchi, Naoko,Kobayashi, Yumi
, p. 615 - 617 (2007/10/02)
The reduction of the nitro group of aromatic nitro compounds with baker's yeast was strongly influenced by the nature of the substituent on nitrobenzene, and in the reaction of acyl nitrobenzenes, selective reduction occurred to give optically active nitro alcohol and amino alcohol and amino ketone without giving any amino alcohol.Keywords baker's yeast; nitro compound; selective reduction; acyl nitrobenzene; chiral nitro alcohol
ASYMMETRIC ACYLATION OF ALCOHOLS IN THE PRESENCE OF CHIRAL TERTIARY AMINES
Potapov, V. M.,Dem'yanovich, V. M.,Khlebnikov, V. A.,Koval'skaya, S. S.
, p. 1602 - 1606 (2007/10/02)
The asymmetric acylation of secondary alcohols with acetic anhydride in the presence of chiral tertiary amines, synthesized from S-(-)-α-phenylethylamine, was investigated.The optical yield of the obtained alcohols was not greater than 2.4percent.It was established that in the presence of S-(-)-N,N-dimethyl-α-phenylethylamine the unreacted alcohol is rich in the S isomer.On the basis of this relationship the S configuration was proposed for (-)-4-iodo-, (-)-4-chloro-, and (-)-3-nitrophenylehanols.
