1252823-79-2Relevant academic research and scientific papers
Study of the nucleophilic behaviour of N-phenylbenzamidine towards 1,2-diaza-1,3-dienes: Domino reactions for imidazole scaffolds
Attanasi, Orazio A.,Bartoccini, Silvia,Giorgi, Gianluca,Mantellini, Fabio,Perrulli, Francesca R.,Santeusanio, Stefania
experimental part, p. 5121 - 5129 (2010/08/20)
Depending on the nature of the solvent, alcohol or DMF, N-phenylbenzamidine shows different nudeophilic behaviour towards the conjugated azoene system of 1,2-diaza-1,3-dienes. In alcohol it reacts as a nucleophile through the N-phenyl imino nitrogen affording spiro pyrroloimidazoles and 1,3-diphenyl- IH-imidazoles. In DMF, by contrast, it behaves as nucleophile mainly by means of the imino amidino nitrogen providing 2-phenylimidazole derivatives by loss of the aniline molecule.
