125288-38-2Relevant academic research and scientific papers
Efficient Activation of Acetals toward Nucleophiles by the Use of Transition Metal Salts. New Method for Cyanation of Acetals and Orthoester Derived from Aromatic and α,β-Unsaturated Carbonyl Compounds with Trimethylsilyl Cyanide under Neutral Condition
Mukaiyama, Teruaki,Soga, Tsunehiko,Takenoshita, Haruhiro
, p. 997 - 1000 (2007/10/02)
In the presence of a catalytic amount of transition metal salts (NiCl2, CoCl2, PdCl2, etc.), trimethylsilyl cyanide smoothly reacts with acetals or orthoester derived from aromatic and α,β-unsaturated carbonyl compounds to give the corresponding α-cyano d
