125313-57-7Relevant articles and documents
A new one step synthesis of maleimides by condensation of glyoxylate esters with acetamides
Faul, Margaret M.,Winneroski, Leonard L.,Krumrich, Christine A.
, p. 1109 - 1112 (1999)
Bisphenyl, bisheteroaryl, indolylaryl and indolylcycloalkyl maleimides are prepared in one step and 67-99% yield by condensation of glyoxylate esters with acetamides using a 1.0 M solution of potassium tert-butoxide in THF. The mechanism of the reaction is discussed.
Fluorescence and chemiluminescence properties of indolylmaleimides: Experimental and theoretical studies
Nakazono, Manabu,Jinguji, Ai,Nanbu, Shinkoh,Kuwano, Ryoichi,Zheng, Zilong,Saita, Kenichiro,Oshikawa, Yuji,Mikuni, Yuta,Murakami, Tatsuhiro,Zhao, Yi,Sasaki, Shigeki,Zaitsu, Kiyoshi
experimental part, p. 9783 - 9793 (2011/04/25)
Various indolylmaleimides (IMs) were synthesized, and their fluorescence (FL) and chemiluminescence (CL) were measured. The substitution at the 2-position of the indole ring and the 3- or 4-position of the maleimide moiety caused an obvious change in the
Aryl[a]pyrrolo[3,4-c]carbazoles as selective Cyclin D1-CDK4 inhibitors
Sanchez-Martinez, Concha,Shih, Chuan,Faul, Margaret M.,Zhu, Guoxin,Paal, Michael,Somoza, Carmen,Li, Tiechao,Kumrich, Christine A.,Winneroski, Leonard L.,Xun, Zhou,Brooks, Harold B.,Patel, Bharvin K. R.,Schultz, Richard M.,DeHahn, Tammy B.,Spencer, Charles D.,Watkins, Scott A.,Considine, Eileen,Dempsey, Jack A.,Ogg, Catherine A.,Campbell, Robert M.,Anderson, Bryan A.,Wagner, Jill
, p. 3835 - 3839 (2007/10/03)
The synthesis of new analogues of Arcyriaflavin A in which one indole ring is replaced by an aryl or heteroaryl ring is described. These new series of aryl[a]pyrrolo[3,4-c]carbazoles were evaluated as inhibitors of Cyclin D1-CDK4. A potent and selective D
