125318-40-3

Upstream product

• 125318-39-0 (1'R,2'R,4E)-1-(2'-formyl-1',2'-dimethyl-2'-hydroxymethylcyclopentyl)-6-<2,5-bis(methoxymethoxy)-3-methylpehnyl>-4-methyl-4-hexen-2-yl pivalate 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 125318-22-1 (1R*,6R*)-1,6-dimethyl-3-oxabicyclo<4.3.0>nonan-4-one 
• 130735-38-5 (1R,2R)-2-t-butyldimethylsiloxymethyl-1,2-dimethylcyclopentaneethanol 
• 130852-39-0 (1R,2R)-2-t-butyldimethylsiloxymethyl-1,2-dimethylcyclopentaneacetaldehyde 
• 125318-28-7 (1'R,2'R)-3-(2'-t-butyldimethylsiloxymethyl-1',2'-dimethylcyclopentyl)-2-hydroxypropanenitrile 
• 125318-27-6 3-[(1R,2R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-1,2-dimethyl-cyclopentyl]-2-trimethylsilanyloxy-propionitrile 
• 125318-19-6 (1'R,2'R)-3-(2'-t-butyldimethylsiloxymethyl-1',2'-dimethylcyclopentyl)-2-(ethoxyethoxy)propanenitrile 
• 130735-35-2 (1R*,2R*)-1,2-dimethyl-2-(2-triphenylmethoxyethyl)cyclopentanecarbaldehyde 
• 130735-37-4 (1R,2R)-1-t-butyldimethylsiloxymethyl-1,2-dimethyl-2-(2-triphenylmethoxyethyl)cyclopentane 
• 125318-38-9 (1'R,2'R,4E)-1-(1',2'-dimethyl-2'-hydroxymethylcyclopentyl)-6-<2,5-bis(methoxymethoxy)-3-methylpehnyl>-4-methyl-4-hexen-2-yl pivalate 
• 125318-36-7 (1'R,2'R,4E)-1-(2'-t-butyldimethylsiloxymethyl-1',2'-dimethylcyclopentyl)-6-<2,5-bis(methoxymethoxy)-3-methylphenyl>-4-methyl-4-hexen-2-ol 
• 130852-41-4 (1'R,2'R,4E)-1-(2'-t-butyldimethylsiloxymethyl-1',2'-dimethylcyclopentyl)-6-<2,5-bis(methoxymethoxy)-3-methylphenyl>-4-methyl-4-hexen-2-one 
• 125318-37-8 (1'R,2'R,4E)-1-(2'-t-butyldimethylsiloxymethyl-1',2'-dimethylcyclopentyl)-6-<2,5-bis(methoxymethoxy)-3-methylphenyl>-4-methyl-4-hexen-2-yl pivalate 

Downstream Products

• 125318-43-6 (Z)-6-(2,5-Bis-methoxymethoxy-3-methyl-phenyl)-1-[(1S,2S)-2-((E)-4-hydroxy-4-methyl-pent-2-enoyl)-1,2-dimethyl-cyclopentyl]-4-methyl-hex-4-en-2-one 
• 75872-68-3 (1'R*,2'R*,2E'')-(Z)-6-(2,5-dihydroxy-3-methylphenyl)-1-<1',2'-dimethyl-2'-(4''-hydroxy-4''-methyl-2''-pentenoyl)-cyclopentyl>-4-methyl-4-hexen-2-one 
• 125318-45-8 (1'R*,2'R*,2E'')-(Z)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<2'-(1'',4''-dihydroxy-4''-methyl-2''-pentenyl)-1',2'-dimethylcyclopentyl>-4-methyl-4-hexen-2-ol 
• 125318-46-9 (1'R*,2'R*,2E'')-(Z)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<1',2'-dimethyl-2'-(4''-hydroxy-4''-methyl-2''-pentenoyl)cyclopentyl>-4-methyl-4-hexen-2-one 
• 125318-44-7 (1'R*,2'R*)-(Z)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<2'-(1,4-dihydroxy-4-methyl-2-pentynyl)-1',2'-dimethylcyclopentyl>-4-methyl-4-hexen-2-yl pivalate 
• 75872-68-3 (1'R*,2'R*,2E'')-(E)-6-(2,5-dihydroxy-3-methylphenyl)-1-<1',2'-dimethyl-2'-(4''-hydroxy-4''-methyl-2''-pentenoyl)-cyclopentyl>-4-methyl-4-hexen-2-one 
• 125318-45-8 (1'R*,2'R*,2E'')-(E)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<2'-(1'',4''-dihydroxy-4''-methyl-2''-pentenyl)-1',2'-dimethylcyclopentyl>-4-methyl-4-hexen-2-ol 
• 125318-46-9 (1'R*,2'R*,2E'')-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<1',2'-dimethyl-2'-(4''-hydroxy-4''-methyl-2''-pentenoyl)cyclopentyl>-4-methyl-4-hexen-2-one 
• 125318-44-7 (1'R*,2'R*)-(E)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<2'-(1,4-dihydroxy-4-methyl-2-pentynyl)-1',2'-dimethylcyclopentyl>-4-methyl-4-hexen-2-yl pivalate 
• 125318-41-4 2,2-Dimethyl-propionic acid (E)-1-[(1S,2S)-2-(1,4-dihydroxy-4-methyl-pent-2-ynyl)-1,2-dimethyl-cyclopentylmethyl]-5-(2,5-dihydroxy-3-methyl-phenyl)-3-methyl-pent-3-enyl ester 
• 125318-41-4 (1'R*,2'R*,4Z)-1-<2'-(1,4-dihydroxy-4-methyl-2-pentynyl)-1',2'-dimethylcyclopentyl>-6-(2,5-dihidroxy-3-methylphenyl)-4-methyl-4-hexen-2-yl pivalate 
• 125318-42-5 (E)-1-{(1S,2S)-2-[(Z)-6-(2,5-Bis-methoxymethoxy-3-methyl-phenyl)-2-hydroxy-4-methyl-hex-4-enyl]-1,2-dimethyl-cyclopentyl}-4-methyl-pent-2-ene-1,4-diol 
• 110351-79-6 (1'R,2'R)-bifurcarenone 
• 130852-46-9 (1'R,2'R,2''E,4E)-6-(5-t-butyldimethylsiloxy-2-hydroxy-3-methylphenyl)-1-<1',2'-dimethyl-2'-(4''-hydroxy-4''-methyl-2''-pentenoyl)cyclopentyl>-4-methyl-4-hexen-2-one 

Relevant academic research and scientific papers

DETERMINATION OF THE ABSOLUTE CONFIGURATION OF BIFURCARENONE BY THE SYNTHESIS OF ITS (1'R,2'R)-ISOMER

(1'R,2'R)-Isomer of bifurcarenone (1) was synthesized.By comparing its ORD spectrum with that of the natural product, the marine C27 hydroquinone isolated as an inhibitor of mitoic cell division was shown to be (1'S,2'S)-1.

SYNTHESIS AND STRUCTURE REVISION OF BIFURCARENONE, A UNIQOE MONOCYCLIC DITERPENE IN COMBINATION WITH A HYDROQUINONE C7 UNIT AS AN INHIBITOR OF MITOTIC CELL DIVISION

Bifurcarenone, a C27 hydroquinone isolated from the brown seaweed Bifurcaria galapegensis, was synthesized as its racemate, and shown to be 2.The structure 1, originally proposed for bifurcarenone, was synthesized, and found to be different from the natur