1253383-91-3 Usage
Uses
Used in Pharmaceutical Industry:
5-Fluoro-6-methylnicotinic acid methyl ester is used as a reactant for the preparation of RORγ inhibitors containing sulfonyl in their structure. These RORγ inhibitors are of interest due to their potential role in modulating immune responses and treating various inflammatory and autoimmune diseases.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-fluoro-6-methylnicotinic acid methyl ester is utilized as a building block for the development of novel therapeutic agents. Its unique structural features allow for the creation of diverse chemical libraries, which can be screened for potential biological activities and further optimized for improved potency and selectivity.
Used in Drug Design and Optimization:
5-Fluoro-6-methylnicotinic acid methyl ester is employed as a starting material in the design and optimization of new drugs targeting specific receptors or enzymes. Its chemical versatility enables the generation of a wide range of analogs with varying pharmacological properties, which can be evaluated for their efficacy and safety in preclinical and clinical studies.
Used in Chemical Research:
In addition to its applications in the pharmaceutical industry, 5-fluoro-6-methylnicotinic acid methyl ester is also used in academic and industrial research settings. It serves as a valuable tool for studying the structure-activity relationships of various bioactive molecules and for exploring new synthetic routes and methodologies in organic chemistry.
Overall, 5-fluoro-6-methylnicotinic acid methyl ester is a versatile and valuable compound with a wide range of applications in the fields of pharmaceuticals, medicinal chemistry, drug design, and chemical research. Its unique structural features and synthetic utility make it an important player in the development of new therapeutic agents and the advancement of our understanding of chemical and biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1253383-91-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,3,3,8 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1253383-91:
(9*1)+(8*2)+(7*5)+(6*3)+(5*3)+(4*8)+(3*3)+(2*9)+(1*1)=153
153 % 10 = 3
So 1253383-91-3 is a valid CAS Registry Number.
1253383-91-3Relevant academic research and scientific papers
5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF
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Paragraph 00161-00164, (2021/04/10)
Provided herein is a compound of Formula (I), or pharmaceutically acceptable salt thereof, wherein R1, Y, X, and n are defined herein. Also provided herein are compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt thereof, e.g., in the treatment of heart disease.
Novel compounds
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, (2017/09/27)
The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
NOVEL COMPOUNDS
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, (2015/12/17)
The preseent invention relates to novel retinoid-related orphan receptor gamma(RORγ)modulators and their use in the treatment ofdiseases mediated by RORγ.
NOVEL COMPOUNDS
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, (2015/12/18)
The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
NOVEL COMPOUNDS
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, (2015/12/17)
Disclosed are novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
CXCR3 RECEPTOR ANTAGONISTS
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, (2010/11/17)
The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 to R6, A, B, X, Y and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
