1253393-98-4

Basic information

• Product Name: C₁₄H₁₈ClN₃O₂
• CAS NO: 1253393-98-4
• Molecular Weight: 295.769
• Mol File: 1253393-98-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₈ClN₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₈ClN₃O₂(1253393-98-4)
• EPA Substance Registry System: C₁₄H₁₈ClN₃O₂(1253393-98-4)

Safety Data

• Hazardous Substances Data: 1253393-98-4(Hazardous Substances Data)

Upstream product

• 41838-46-4 4-Amino-1-methylpiperidine 
• 17738-71-5 2-((4-chlorophenyl)-amino)-2-oxoacetic acid 

Relevant articles and documents

CD4 mimics targeting the HIV entry mechanism and their hybrid molecules with a CXCR4 antagonist

Small molecules behaving as CD4 mimics were previously reported as HIV-1 entry inhibitors that block the gp120-CD4 interaction and induce a conformational change in gp120, exposing its co-receptor-binding site. A structure-activity relationship (SAR) study of a series of CD4 mimic analogs was conducted to investigate the contribution from the piperidine moiety of CD4 mimic 1 to anti-HIV activity, cytotoxicity, and CD4 mimicry effects on conformational changes of gp120. In addition, several hybrid molecules based on conjugation of a CD4 mimic analog with a selective CXCR4 antagonist were also synthesized and their utility evaluated.