1253396-39-2Relevant academic research and scientific papers
One-pot double Suzuki couplings of dichloropyrimidines
Anderson, Samantha C.,Handy, Scott T.
, p. 2721 - 2724 (2010)
An effective one-pot, regioselective double Suzuki coupling of 2,4-dichloropyrimidine has been developed, which enables the quick and efficient synthesis of diarylated pyrimidines. The choice of solvent proved critical to the success of this reaction sequence, with alcoholic solvent mixtures affording much greater reactivity and requiring correspondingly lower temperatures than the use of polar aprotic solvents. Georg Thieme Verlag Stuttgart.
