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Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl(9CI) is a chemical compound derived from the nucleoside uridine, which is a component of RNA. This modified compound is distinguished by the lack of hydroxyl groups at the 2' and 3' positions, replaced instead with difluoro and methyl groups respectively. These structural alterations confer upon it the potential to act as an antiviral agent by disrupting the replication of viral RNA and inhibiting enzymes crucial for DNA and RNA synthesis.

125362-07-4

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125362-07-4 Usage

Uses

Used in Pharmaceutical Industry:
Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl(9CI) is used as a potential antiviral agent for its ability to interfere with the replication process of viral RNA, thereby inhibiting the proliferation of viruses.
Used in Biochemical Research:
In the field of biochemical research, Uridine,2',3'-dideoxy-2',3'-difluoro-5-methyl- (9CI) serves as a valuable tool for studying the mechanisms of RNA and DNA synthesis, as well as the activity of enzymes involved in these processes.
Further research is necessary to explore the full spectrum of applications and effects of Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl(9CI), including its potential role in the development of new antiviral therapies and its utility in understanding fundamental aspects of nucleic acid metabolism.

Check Digit Verification of cas no

The CAS Registry Mumber 125362-07-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,3,6 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125362-07:
(8*1)+(7*2)+(6*5)+(5*3)+(4*6)+(3*2)+(2*0)+(1*7)=104
104 % 10 = 4
So 125362-07-4 is a valid CAS Registry Number.

125362-07-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 2'-F-ribo-FLT

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125362-07-4 SDS

125362-07-4Downstream Products

125362-07-4Relevant academic research and scientific papers

SYNTHESIS OF 2',3'-DISUBSTITUTED 3'-DEOXYTHYMIDINE DERIVATIVES

Herdewijn, P.,Aerschot, A. Van

, p. 943 - 948 (2007/10/02)

Reaction of 2 with DAST followed by detritylation and monomethoxytritylation afforded 34percent of the fluorinated nucleoside 3.This intermediate was used to prepare the 3'-azido-2'-fluoro- and 2',3'-difluoro substituted 5-methyluridine analogues 7 and 11, respectively.

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