1254036-71-9 Usage
Uses
Used in Pharmaceutical Industry:
6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole is used as a potential pharmaceutical agent for its possible interaction with biological systems. 6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole's unique structure allows it to be a candidate for further studies in drug discovery, potentially leading to the development of new medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole serves as a subject for investigation. Its heterocyclic nature and the presence of multiple rings make it an interesting molecule to explore for its potential therapeutic properties and mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 1254036-71-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,0,3 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1254036-71:
(9*1)+(8*2)+(7*5)+(6*4)+(5*0)+(4*3)+(3*6)+(2*7)+(1*1)=129
129 % 10 = 9
So 1254036-71-9 is a valid CAS Registry Number.
1254036-71-9Relevant academic research and scientific papers
Application of C-H Functionalization in the Development of a Concise and Convergent Route to the Phosphatidylinositol-3-kinase Delta Inhibitor Nemiralisib
Bream, Robert N.,Clark, Hugh,Edney, Dean,Harsanyi, Antal,Hayler, John,Ironmonger, Alan,Mc Cleary, Nadine,Phillips, Natalie,Priestley, Catherine,Roberts, Alastair,Rushworth, Philip,Szeto, Peter,Webb, Michael R.,Wheelhouse, Katherine
, p. 529 - 540 (2021/03/01)
This paper describes the development of an improved and scalable method for the manufacture of nemiralisib, a phosphatidylinositol-3-kinase delta inhibitor. Incorporation of three consecutive catalytic reactions, including a palladium-catalyzed C-H functionalization and an iridium-catalyzed borylation, significantly simplified and shortened the synthetic sequence. The revised route was successfully implemented in a pilot plant on a multikilogram scale to deliver >100 kg of product.
