125404-46-8Relevant academic research and scientific papers
Absolute Stereochemistry of the Novel Dioxaspiro Diterpenoids Strictanonic and Grindelistrictic Acids. Stereoselective Synthesis of Strictanonic Acid Methyl Ester and its C-6 Epimer
Gonzalez-Sierra, Manuel,Olivieri, Alejandro C.,Colombo, Maria I.,Ruveda, Edmundo A.
, p. 1393 - 1399 (2007/10/02)
The stereoselective synthesis of (+)-strictanonic acid methyl ester (2b) and its C-6 epimer from a common chiral intermediate, derived from natural grindelic acid (1a) of known absulute configuration, is described.With the aid of one- and two-dimensional multipulse n.m.r. techniques, the complete stereochemistry of strictanonic acid and that of C-9 of the related bisnorditerpene grindelistrictic acid (6a) was established.
