1254124-92-9Relevant academic research and scientific papers
Manganese η2-complexes as auxiliaries for stereoselective aldol synthesis of allenyl carbinols
Bhowmick, Manishabrata,Lepore, Salvatore D.
, p. 5078 - 5080 (2010)
A convenient and robust manganese auxiliary was linked via an η2-bond to alkynyl esters and ketones using a mild complexation reaction with methylcyclopentadienyl manganese tricarbonyl. This complex readily underwent aldol reactions with exclusive α-substitution and in good diastereoselectivities especially with aryl ketone substrates. This selectivity has been rationalized using a cyclic transition state model in which the manganese auxiliary plays a critical role in promoting E(O)-geometry of the cumulenolate intermediate.
