83354-06-7Relevant academic research and scientific papers
Recyclable heterogeneous palladium-catalyzed carbonylative Sonogashira coupling under CO gas-free conditions
Zhou, Zebiao,Li, Jianying,Xu, Zhaotao,Cai, Mingzhong
, p. 2015 - 2025 (2020)
A convenient, efficient and practical heterogeneous palladium-catalyzed carbonylative Sonogashira coupling of aryl iodides with terminal alkynes under CO gas-free conditions has been developed by using an MCM-41-supported bidentate phosphine palladium ace
Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source
Lyu, Xue,Sun, Guanglong,Zhou, Yang,Wang, Yingying,Lei, Min,Wu, Wanying,Guo, Dean
, p. 309 - 315 (2019/01/21)
Abstract: A practical and efficient palladium-catalyzed carbonylative Sonogashira cross-coupling reaction for the synthesis of alkynones from aryl iodides, alkynes, and formic acid as the CO source has been described. Under the assistance of PPh3/I2, formic acid can be used as the CO source for synthesis of alkynones in moderate–good yields. Furthermore, it is also successfully applied for the modification of natural products, such as vindoline and tabersonin, to obtain the corresponding products.
A Convenient and Efficient Palladium-Catalyzed Carbonylative Sonogashira Transformation with Formic Acid as the CO Source
Peng, Jin-Bao,Wu, Fu-Peng,Li, Chong-Liang,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 1434 - 1437 (2017/04/01)
A practical, convenient, and efficient palladium-catalyzed carbonylative Sonogashira reaction of aryl iodides was developed. With formic acid as the CO source and dicyclohexylcarbodiimide as the activator, various alkynones were produced in good to excell
Palladium anchored on amine-functionalized K10 as an efficient, heterogeneous and reusable catalyst for carbonylative Sonogashira reaction
Chavan, Sujit P.,Varadwaj, G.Bishwa Bidita,Parida, Kulamani,Bhanage, Bhalchandra M.
, p. 237 - 245 (2015/10/12)
The present work describes the immobilization of palladium chloride (II) on the amine functionalized K10 support and its application toward the carbonylative Sonogashira reactions. The various catalyst characterization techniques revealed the successful grafting of APTES moiety on the K10 clay surface through covalent bonding and Pd with the NH2 groups of APTES@K10 through co-ordinate bonding. The immobilized catalyst was successively applied for copper and phosphine free carbonylative Sonogashira reaction of aryl and hetero aryl iodides with terminal alkynes. To our delight, the electron withdrawing aryl halides can be efficiently utilized as an electrophiles giving higher selectivity toward carbonylated products. Moreover, dibenzoylmethane which is a potential synthetic intermediate in organic transformation has been also synthesized using this protocol. Recovery of catalyst by simple filtration and its reuse up to four consecutive cycles ensure the robustness of present catalytic protocol.
Palladium-catalyzed carbonylative coupling of aryl iodides and benzyl acetylenes to 3-alkylidenefuran-2-ones under mild conditions and its density functional theory modeling
Wu, Xiao-Feng,Jiao, Haijun,Neumann, Helfried,Beller, Matthias
, p. 16177 - 16185 (2013/02/22)
A general and efficient method for the palladium-catalyzed carbonylative coupling of aryl iodides to benzyl acetylenes has been developed. Various furanones have been prepared in excellent yields from their corresponding benzyl acetylenes at room temperat
Convenient and general palladium-catalyzed carbonylative sonogashira coupling of aryl amines
Wu, Xiao-Feng,Neumann, Helfried,Beller, Matthias
experimental part, p. 11142 - 11146 (2012/02/03)
Bar (alky)none: A general and efficient method for carbonylative Sonogashira coupling reactions of anilines to generate alkynones has been developed (see scheme; TFP=tri(2-furyl)phosphine). The reaction proceeds under mild conditions and no base is needed
