125422-64-2Relevant academic research and scientific papers
Regio-Control of Formal Cycloadditions of 5-Alkoxyoxazoles with Diethyl Oxomalonate
Suga, Hiroyuki,Shi, Xiaolan,Ibata, Toshikazu
, p. 1673 - 1676 (1994)
Tin(IV) chloride-catalyzed formal cycloadditions of 5-alkoxy-2-(p-methoxyphenyl)- or 2-phenyloxazoles with diethyl oxomalonate gave 2-oxazoline-4,5,5-tricarboxylates in high regioselectivity. 4-Substituted 5-alkoxy-2-methyloxazoles showed a trend to
DO OXAZOLES UNDERGO DIELS-ALDER REACTIONS WITH HETERODIENOPHILES ?
Hassner, Alfred,Fischer, Bilha
, p. 3535 - 3546 (2007/10/02)
5-Alkoxy and 2-alkoxyoxazoles wre shown to react with N=N, C=N or C=O dienophiles to form products that in most cases can be explained to result from a Diels-Alder addition, or by nucleophilic attack of the oxazole on the dienophile, followed by rearrangement.The products are triazolines, imidazolines or oxazolines respectively.Relative reactivities were established and mechanistic pathways discussed.
