1254229-85-0

Basic information

• Product Name: N-([2-⁽²⁾H]-1-(2-phenylethyl)-4-piperidinyl)aniline
• Synonyms: N-([2-⁽²⁾H]-1-(2-phenylethyl)-4-piperidinyl)aniline
• CAS NO: 1254229-85-0
• Molecular Weight: 281.405
• Mol File: 1254229-85-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-([2-⁽²⁾H]-1-(2-phenylethyl)-4-piperidinyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-([2-⁽²⁾H]-1-(2-phenylethyl)-4-piperidinyl)aniline(1254229-85-0)
• EPA Substance Registry System: N-([2-⁽²⁾H]-1-(2-phenylethyl)-4-piperidinyl)aniline(1254229-85-0)

Safety Data

• Hazardous Substances Data: 1254229-85-0(Hazardous Substances Data)

Upstream product

• 85893-37-4 fentanyl N-oxide 
• 437-38-7 N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide 
• 1254229-86-1 C₂₂H₂₇⁽²⁾HN₂O 

Relevant articles and documents

Identification of isobaric product ions in electrospray ionization mass spectra of fentanyl using multistage mass spectrometry and deuterium labeling

Isobaric product ions cannot be differentiated by exact mass determinations, although in some cases deuterium labeling can provide useful structural information for identifying isobaric ions. Proposed fragmentation pathways of fentanyl were investigated by electrospray ionization ion trap mass spectrometry coupled with deuterium labeling experiments and spectra of regiospecific deuterium labeled analogs. The major product ion of fentanyl under tandem mass spectrometry (MS/MS) conditions (m/z 188) was accounted for by a neutral loss of N-phenylpropanamide. 1-(2-Phenylethyl)- 1,2,3,6-tetrahydropyridine (1) was proposed as the structure of the product ion. However, further fragmentation (MS3) of the fentanyl m/z 188 ion gave product ions that were different from the product ion in the MS/MS fragmentation of synthesized 1, suggesting that the m/z 188 product ion from fentanyl includes an isobaric structure different from the structure of 1. MS/MS fragmentation of fentanyl in deuterium oxide moved one of the isobars to 1Da higher mass, and left the other isobar unchanged in mass. Multistage mass spectral data from deuterium-labeled proposed isobaric structures provided support for two fragmentation pathways. The results illustrate the utility of multistage mass spectrometry and deuterium labeling in structural assignment of isobaric product ions.