125440-15-5

Basic information

• Product Name: 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>thymine
• Synonyms: 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>thymine
• CAS NO: 125440-15-5
• Molecular Weight: 619.694
• Mol File: 125440-15-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>thymine(125440-15-5)
• EPA Substance Registry System: 1-<5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-β-D-erythro-pentofuranosyl>thymine(125440-15-5)

Safety Data

• Hazardous Substances Data: 125440-15-5(Hazardous Substances Data)

Upstream product

• 115728-43-3 5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-D-threo-pentonic acid γ-lactone 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 115728-44-4 5-O-(tert-butyldiphenylsilyl)-3-deoxy-2-Se-phenyl-2-seleno-D-erythro-pentonic acid γ-lactone 
• 125440-13-3 (S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-trimethylsilanyloxy-2,3-dihydro-furan 
• 102717-29-3 (5S)-5-({[tert-butyl(diphenyl)silyl]oxy}methyl)dihydrofuran-2(3H)-one 
• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 
• 187843-66-9 tert-Butyl-diphenyl-((2S,5S)-5-phenylselanyl-tetrahydro-furan-2-ylmethoxy)-silane 
• 187843-63-6 tert-Butyl-diphenyl-((2S,5R)-5-phenylselanyl-tetrahydro-furan-2-ylmethoxy)-silane 
• 149656-26-8 1-O-acetyl-5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-2-(phenylselenenyl)-D-erythro-pentafuranose 
• 5707-04-0 Phenylselenyl chloride 
• 149204-36-4 (1S)-1-<<(tert-butyldiphenylsilyl)oxy>methyl>-2,3-dihydrofuran 
• 3444-09-5 1,3-bis(trimethylsilyl)thymine 
• 65-71-4 thymin 

Downstream Products

• 3416-05-5 3'-Deoxythymidine 
• 3056-17-5 stavudin 
• 125440-17-7 1-<5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pento-2-enofuranosyl>thymine 
• 121687-74-9 1-<5-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-glycero-pentofuranosyl>thymine 

Relevant articles and documents

Stereoselective synthesis of 2',3'-dideoxynucleosides by addition of selenium electrophiles to glycals. A formal synthesis of D4T from 2-deoxyribose

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A Highly Stereoselective Glycosylation of 2-(Phenylselenenyl)-2,3-dideoxyribose Derivative with Thymine: Synthesis of 3'-Deoxy-2',3'-didehydrothymidine and 3'-Deoxythymidine

A highly stereoselective synthesis of 3'-deoxy-2',3'-didehydrothymidine (D4T) and 3'-deoxythymidine (D2T) was achieved from the condensation of 2-(phenylselenenyl)-2,3-dideoxyribose derivative and silylated thymine in the presence of trimethylsilyl triflate.