125476-63-3Relevant academic research and scientific papers
Enantioselective Saponification of Substituted, Achiral 3-Acyloxy-propionates with Lipases: Synthesis of Chiral Derivatives of "Tris(hydroxymethyl)methane"
Ehrler, Juerg,Seebach, Dieter
, p. 379 - 388 (2007/10/02)
Ethyl 3-hydroxy-2-(hydroxymethyl)propionate (11) was synthesized with an overall yield of 40percent starting from the pentaerythritol derivative 5,5-bis(hydroxymethyl)-1,3-dioxane (7).Both OH-groups of 11 were acetylated (ethanoyl, propanoyl, butanoyl, he
