1254781-42-4

Basic information

• Product Name: 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester
• Synonyms: 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester
• CAS NO: 1254781-42-4
• Molecular Weight: 444.462
• Mol File: 1254781-42-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester(1254781-42-4)
• EPA Substance Registry System: 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester(1254781-42-4)

Safety Data

• Hazardous Substances Data: 1254781-42-4(Hazardous Substances Data)

Upstream product

• 1240402-79-2 [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol 
• 65275-12-9 5-hydroxy-2-picolinic acid ethyl ester 

Downstream Products

• 1254781-43-5 5-[3-(4-fluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester 

Relevant articles and documents

ISOXAZOLE-PYRIDINE DERIVATIVES

The present invention is concerned with isoxazole-pyridine derivatives of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.