1240402-79-2

Basic information

• Product Name: [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol
• Synonyms: [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol
• CAS NO: 1240402-79-2
• Molecular Weight: 295.313
• Mol File: 1240402-79-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol(1240402-79-2)
• EPA Substance Registry System: [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol(1240402-79-2)

Safety Data

• Hazardous Substances Data: 1240402-79-2(Hazardous Substances Data)

Upstream product

• 1240402-78-1 3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazole-4-carboxylic acid 
• 100-52-7 benzaldehyde 
• 954230-39-8 3-(4-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester 

Downstream Products

• 1240402-80-5 3-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-isoxazole-5-carboxylic acid methyl ester 
• 1246924-65-1 6-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester 
• 1254966-30-7 5-[3-(4-fluoro-phenyl)-5-formyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 
• 1254966-33-0 5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid 
• 1254965-32-6 5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid amide 
• 1254966-32-9 5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 
• 1254965-36-0 rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide 
• 1254966-31-8 5-[5-((1S,2R)-1,2-dihydroxy-2-phenyl-ethyl)-3-(4-fluoro-phenyl)-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 
• 1254781-42-4 5-[3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-ylmethoxy]-pyridine-2-carboxylic acid ethyl ester 

Relevant articles and documents

ISOXAZOLE-ISOXAZOLES AND ISOXAZOLE-ISOTHIAZOLES

The present invention is concerned with isoxazole-isoxazoles and isoxazole-isothiazoles of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as cognitive enhancers or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.

ISOXAZOLE-PYRIDINE DERIVATIVES

The present invention is concerned with isoxazole-pyridine derivatives of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.