125488-46-2Relevant academic research and scientific papers
Free radical-promoted conjugate addition of activated bromo compounds using titanocene(III) chloride as the radical initiator
Mandal, Samir Kumar,Jana, Samaraesh,Roy, Subhas Chandra
, p. 6115 - 6117 (2005)
Free radical-promoted conjugate addition of activated bromo compounds to α,β-unsaturated ketones and reactive α,β-unsaturated esters has been described using titanocene(III) chloride (Cp2TiCl) as the radical initiator. Cp2TiCl was prepared in situ from commercially available Cp2TiCl2 and activated zinc dust in THF.
Generation of organotantalum reagents and conjugate addition to enones
Shibata, Ikuya,Kano, Takeyoshi,Kanazawa, Nobuaki,Fukuoka, Shoji,Baba, Akio
, p. 1389 - 1392 (2007/10/03)
A superior method of conjugate allylation: The transmetalation of allyltin compounds with TaCl5 yielded active tantalum reagents for conjugate addition to enones. Even bulky allyl moieties could be introduced to enones in this manner (see scheme). Both cyclic and acyclic enones reacted facilely under extremely mild conditions.
An Effective and Selective Conjugate Propargylation Reaction of Stannylallenes to α,β-Unsaturated Carbonyl Compounds and α-Nitro Olefins
Haruta, Jun-ichi,Nishi, Koichi,Matsuda, Satoshi,Akai, Shuji,Tamura, Yasumitsu,Kita, Yasuyuki
, p. 4853 - 4859 (2007/10/02)
Stannylallenes (1) reacted with α,β-unsaturated carbonyl compounds and α-nitro olefins in the presence of TiCl4 to give the corresponding conjugate propargylation products.Thus, the reaction of 1 with cyclic and acyclic α,β-unsaturated carbonyl compounds (2) gave β-propargylic ketones (3) in high yields.With α-nitro olefins (4), two types of products, β-propargylic nitroalkanes (5) and α-propargylic ketones (6), were obtained selectively depending on the presence or absence of the α-substituent of 4.Transformation of the products (6) to cyclopentenone derivatives (10 and 12) are also described.
TiCl4-mediated Conjugate Addition Rections of Stannylallenes to α,β-Unsaturated Carbonyl Compounds
Haruta, Jun-ichi,Nishi, Koichi,Matsuda, Satoshi,Tamura, Yasumitsu,Kita, Yasuyuki
, p. 1065 - 1066 (2007/10/02)
Stannylallene reacted with α,β-unsaturated carbonyl compounds in the presence of TiCl4 to give the corresponding conjugate addition products, β-prop-2-ynylic carbonyl compounds.
