1254981-31-1

Basic information

• Product Name: 2'-chloro-4-fluoro-4-phenyl-3'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl
• Synonyms: 2'-chloro-4-fluoro-4-phenyl-3'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl
• CAS NO: 1254981-31-1
• Molecular Weight: 358.766
• Mol File: 1254981-31-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2'-chloro-4-fluoro-4-phenyl-3'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-chloro-4-fluoro-4-phenyl-3'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl(1254981-31-1)
• EPA Substance Registry System: 2'-chloro-4-fluoro-4-phenyl-3'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl(1254981-31-1)

Safety Data

• Hazardous Substances Data: 1254981-31-1(Hazardous Substances Data)

Upstream product

• 1056382-25-2 4-fluoro-4-phenylpiperidine hydrochloride 
• 1186194-98-8 2,4-dichloro-3-(trifluoromethyl)pyridine 

Downstream Products

• 1254981-32-2 (4-fluoro-4-phenyl-3′-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,4′]bipyridinyl-2′-yl)hydrazine 

Relevant articles and documents

Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8- trifluoromethyl[1,2,4]triazolo[4,3- a ]pyridine (JNJ-42153605): A positive allosteric modulator of the metabotropic glutamate 2 receptor

Advanced leads from a series of 1,2,4-triazolo[4,3-a]pyridines with mGlu2 receptor PAM activity are reported. By modification of the analogous imidazo[1,2-a]pyridine series, the newly reported leads have improved potency, in vitro ADMET, and hERG as well