125520-70-9Relevant academic research and scientific papers
Synthesis of (R)-Lasiodiplodin from Polyhydroxybutyric Acid
Braun, Manfred,Mahler, Ulrike,Houben, Sabine
, p. 513 - 517 (2007/10/02)
The twelve-membered macrolide (R)-lasiodiplodin (1), a fungal metabolite of Botrysdiplodia theobromae, has been synthesized in a nine-step procedure. (R)-1,3-Butanediol (6), which is easily available by reductive depolymerization of the biopolymer polyhydroxybutyric acid (PHB), proves itself as a suitable enantiomerically pure building block.
