1255460-82-2Relevant academic research and scientific papers
One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes
Raimondi, Wilfried,Lettieri, Gregory,Dulcere, Jean-Pierre,Bonne, Damien,Rodriguez, Jean
supporting information; experimental part, p. 7247 - 7249 (2010/11/16)
A new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity. This one-pot process combines an enantioselective organocatalytic Michael addition with a highly diastereoselective [3+2]-cycloaddition-fragmentation step.
